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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f0b455beebbd2217c628343e2393849a41ac4bb1f43d66be49328fc6f7be0a' 
  AND token = '8q/s5pOvCEcsxifjC4PLycJti5H6REZbYbaAhxUJE2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}