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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554c164dd609b8b97aa2667e106eec83c78ae2c4d78b3199d627c8df742c6c30' 
  AND token = 'A7b85cue/BIEVwmzzO36oc0N3Xt6qm8wLaaL3q/Rl8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}