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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37703364d9c03dc2a44b50518d552c3d834484e7e1b235ca52bb8cadc366b096' 
  AND token = 'A2Ud/2M06MCGSTOw/dTSZ2ePZ9sT4+n78iriYesjdu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}