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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075451ad8b9afa32fb6b0aba50778aecc3729bab9db3eaf91ac0d456cb2a9014' 
  AND token = 'fonceBXdhh8W4Lfmsc9XpCTnvP4V4j19PKunHVzWMZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}