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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43edd7813c0756c8e92ac0588df1ddb58c97601013fe504f11d373daf9f5eaeb' 
  AND token = '10V4RD02NeoUp9vdUp+4aMSxTSCxm5yW5zO6HDqkloo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}