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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e306bf95fd9d7f06ab6efdf741b89d269eb40d42b6d44b08e067554f6689d4c' 
  AND token = 'PjxNnw4vS4jxqwvDIZ9wVdSwdr8AYuvp6BCbBHOvjqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}