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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fbb65f51cc681ee9734930ed22835e9f679e2339b7a52fdd3bd0f6f502a3431' 
  AND token = '7dLThdjcJm9x8IOFV9qziMpuF3BAzedBVC9ZZUDVjFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}