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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99379a19011c5acf83e3cb4faad502f534818449c784550ef71c43a69d3b4d30' 
  AND token = 'ijYgCvE2C1GHrdc3ZwSsg7sepnC05KGAjSH1VAGifQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}