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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650d53a7349d7bdbffd61189fae7f60830d3ec51df0cc4d4d719eb97159ce057' 
  AND token = 'ku1favBv2UXKZAYTMBLrWZQjR65cwYvccjndVkQ7E20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}