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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd374f0f3b62baa5c0e968d00e9f7a789bd4aab03c5d200c079114fb6b50c39' 
  AND token = 'I2RQr7Z5DmphGJXbi0Ocp2dANccWbq79C2N6VJmJs0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}