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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd8bb282496eeeeda2e59d8962ba15f6c329593c204c541043bc8a223d88ea6' 
  AND token = 'LcQ2WcIojGuKBL/MlcR1maxFNKuWwYN7Sgdn5yx3HsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}