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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ea1a179d32f5c678abb75a152ca414c5e9ee3cceb74939e0ef222e823b2606' 
  AND token = 'kS9Oym1ayPEHzI2WUK1jHh0TR3f1OBT+IxEC7HYpWV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}