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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590e458bc15ef284f30e28968e0d06875a9c0209034de398fe9442b8b57226e5' 
  AND token = '6PXu3mNHIsYMhXGq8IeZi8y2i/9ccA4b+9oQ0w7SOnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}