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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5edef48c26002e13be7bc94e392d07e3a49a0f970bc9c21e535398b49995a2' 
  AND token = 'Fim1wmCdZKwKKPtbN6i/PJCrz4/fJh8AbI+R/w31n1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}