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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2259fb92f41b2e52b95fe96720e24e061876b6099cc4eb1b949668265880c6e8' 
  AND token = 'VI5sjE+uy3nT+aY70aqA6XLMrGxxeKGpy6JVAAqlREQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}