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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f2f330317c87f255b07818a580f0da0e0dc1cbe147ca4e56a8c1cee514fd3b' 
  AND token = 'kUXGKhZAwPsAiiH47iJGxLkZD+YwSRoLu637DfWRQcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}