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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091528253907e0d999d2a3ca5e90fe2efc429a59b7d099232284d37b2f8f7813' 
  AND token = 'BC5NXP0k+qvkruHV3IAHIfAALlk51VYcSFtTTxBA1Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}