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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0cec16d1c5c95944b018b5c910e44050f8c45d5ab3ccdd61582ecf2801efaab' 
  AND token = 'haTmz5OkuKoN++F1itXsp8FSxbRH+ph3xpkkfOcV7SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}