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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1c74497a4bec72d2385dff8ac73bc1d3548e44c1a818b39472d5f571a4f3b2' 
  AND token = 'XzGUgDd3yjSh4/RlUP7nL4kB2NaIFsGYUUl1ozNmQ8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}