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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e82c783edf9fe446319eca286765f5294aed09efd9fcf0be348c6a65edc3d9a' 
  AND token = 'NzPr+OUL0THnNcqAR/t/TEk6UB7xh1Z40wzv1MPjzcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}