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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6f0b5f5648a167e7bee9cb277c3264074ad8ac73c7e2eb2011178f309c579e' 
  AND token = 'vc4yZPdye54GaQQoj/sH3Sy3nHzOxzYURRIpqmBTIC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}