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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c92d188d1d3e6cf6c4fa7f5ae9d6ea8af0693b25b90def7055ca521b52b2a9d' 
  AND token = 'QJFCwf3f0CuxHpj2y+TszLit4VTiOJ8g/aJ2grtTvac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}