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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21112a64d850ea7b54bc376402a2f1871fc0b07532a5216b274830e61555c70' 
  AND token = 'UXCKtVPl8H2IggjCeGjvCAHhnhIkal57gvi43+IPwcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}