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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae69875db9a8f4fd43a60b241857f70a49587cd2255e74c2438ea79a86ae2ae1' 
  AND token = 'xjGC14uQPFfngSesRPuHTU4NgHk1QWmn5+Ylvq04pqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}