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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e01e64bb567273c225572b5c1b2f33fe460ff0372fe7bf4949f3d9991fb9cba' 
  AND token = 'km0H4RackW/B6S6aGFgeo9FWJlXKzMumSsV46uHd5Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}