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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23288d45b0355bad7e27f1ff908ae446cea56cfc60ce7f005f88632cbaf6e0a7' 
  AND token = 'qsQ8ZFLES4hHa11EMLxm4P3sbKOuHQowR7lEpG/GsTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}