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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae8afd8bdd2180d96b7282379842d75c29f803b5516019c2b05b6ae4fe5d1ec' 
  AND token = 'TOPwTtFT5ZIXAgRI2AXnGr4ao6SCXcZrnY0Gqd7A5Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}