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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9d391654c83ca70af9216b381361e698eb05ab99f2a57ce2d7f09ab8837f25' 
  AND token = '5VzGCSmX34l/e+6qdwobxbMIeXPhfKCJeUyX8An0T40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}