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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f9194d9636cf0ff28ec40670f39086fc85fee24bc5fb541e69d1f5525cc37a' 
  AND token = 'EE77RQsLzMf7Q2QE+veMiYey+5YxvuTsqUGp+qZOfNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}