Sandbox

SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72dfdd6bf9b26be60c1de0d1050ffc2d022cf04ddfbe1b7a23bd4dd152008345' 
  AND token = 'wn5RITabIa9tlwVKzI7e9HRXTOjKeyOen5i/ZmLW/cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}