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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b02b353b9a26192366cdebe49dd1d2183a17cebb0f07dcc645f67389c54355' 
  AND token = 'ci3HQifzsRJ7Lp0VRz1SDabfu/f6h6xiQ0shTHbHhsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}