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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '660dafce6c9aff99d05ce6c2af47ff4cdeaa1b3924db8b0e856891ffe3065866' 
  AND token = 'jJsNeQpSMsUV1Y+BUebZDDn7kS53NHVoJrw2WTf8ZsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}