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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5baa1a4b300be72963c6e282e0733ac80fa68296aa2b4fb91fedbe940fd284' 
  AND token = 'izUgoiKs5iJeXQ0OtWe0jPdMWkWnJwoM9fez/gW7Pfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}