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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa079bc76c3403f36cd96e2a447841304b9840702743c18b805ba8b811621b40' 
  AND token = 'Msqf9jHNqS+ewSEV7pfBQFowfVMcq5sPWzLV6o9DqzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}