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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71377f1faea1ad4b2f2216a8bd33e8463b07d014290f55d1fce58b3544dea01b' 
  AND token = 'b/jKTfmMF1G03z+RL9N1p4LxfHq6v4bGAZlvBC57+Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}