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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220ab5d12a00ea77736811c77fc91f33c9fae0e13017b79cac153e393d67e6b4' 
  AND token = '8kSI9PNIYs9hCCXEa+PymvsXC8sNLWP7SysiDB+PTLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}