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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc0493623b589beb66407b920d29deebfd014b5f66abd09f45c033533fb751f2' 
  AND token = 'MScQ1D4RSHLQ2ZZA1RBI64gYa7Y4MNXnejNnzwwT5Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}