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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '033375bb74e1be9e64b085a415f4b9118401076edc6e52a2d7d4d42cfe8423d2' 
  AND token = 'R1zfIFSsenWq9A9LK4T8gqO5SJh97zQ5txsfB86hvws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}