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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c682d8bc9e53c2b529a3f90c40c6a0feb577fef3b8e2f49e67b9404590161fa0' 
  AND token = 'UqS3rZuMymwMI8b1dfLj8tVW/69QtDDmiGnD9AXsyL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}