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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5246fe32a07c46ae0e86592019693ecbd6513240de9f564ed0f8099c75704cc' 
  AND token = 'e2UX6My3hRYPZoz/k1wg6d+9OQKIe402DSdoMx167LE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}