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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9295cf5d19bd9442160a41e37fd7e92c556ad68a9193e61c5fa74d9967e6e877' 
  AND token = 'GTNiMF2JGqt87euVIoDh5MxRbIdJ+Rl9tJqbhpRM3KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}