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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41195108bf085eb480684643b50021de55364e912b008805a76a609ca1d00434' 
  AND token = 'r+7KE+MDcy1V011UmBAOiffMd5Rx3kiiA8NKrgR5bSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}