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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e1562f0373f630e4c482e7bb0c342a4f1203c9be74982990785d7ed7c938e1' 
  AND token = 'ot3kemFEFrsW1GipSwl0AEetc5DYzYMpYcRHHUouB54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}