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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50165807fc475ae6159f2181b504a11d5114ca004d5dc630fdba14849f21d5df' 
  AND token = 'qdc9J/iHi+Sda7bppgZnrq18kpNdTJCTPqwEKry5ybc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}