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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb7bfd0cd4de6c4226310250bcd2125a58b0e7a392f2a7f756660610169095d' 
  AND token = 'u2hs2DRv/bkOi2OwiTiKYwrl4U8rXfUqTiQqkypMXs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}