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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b451a655ab2a7832dd07344340e4cc07a41b17d19927b69c47fa0c4c97217b5' 
  AND token = 'IQd1VDs6tzmt4bmdP1zO42+vaYEePkNRLcy+DX8h6Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}