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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e6b39164d8ea86e8def30a909ce92f20c5bcba59ceb69d29849b18b770399a' 
  AND token = 'uXUIbHy74G0bHbdDLRLu5jTA8aMxeJ/SxuLDwf2kbeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}