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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b1ccac5aece5776dd4921dba2abc66a91938d6109b48e1312cc6afcff2b1946' 
  AND token = 'I1ihAufB+3KP8/+r0P6zJ2uYI55CURJ9kBRYANmkV8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}