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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88ca912973d2d7fd5e6f45738523bad9110914221287718df8af1b74d195437' 
  AND token = 'wGw7igkqQNDTUlAiUQWcohCfQ0SYtMBMXBO1zQtOoFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}