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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6745a34216e8b6ad8f6dbe3373621cf46f0b0b08d2f061383691178d9839eb9' 
  AND token = '7twqrlnzPhn8MYwBJ9756Dd1osbJcKehncj7YJt0lTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}